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Department of Infectious Diseases and Pathobiology (DIP)
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Gruppe Frey
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Conference contributions presented by B. Lundström-Stadelmann
Keynote: Lundström-Stadelmann B. Metabolism in Parasitic Helminths, Seminar day and user meeting on live-cell metabolic profiling, Bucher Biotec, Bern, Oct. 16, 2024.
Invited Talk: Lundström-Stadelmann B. The quest for new compounds for the treatment of alveolar echinococcosis, Conference on Tropical Medicine and Global Health, Düsseldorf, Germany, Sept 19-21, 2024.
Invited Talk: Lundström-Stadelmann B. Novel drug treatments against alveolar echinococcosis, what is going on
in vitro
and in mouse models. Swiss Echinococcosis network, online meeting, Apr. 16, 2024.
Invited Talk: Lundström-Stadelmann B and Frey C. Top-Sharing. IDEAS Retreat. Ticino, Aug 28, 2023.
Invited Talk: Lundström-Stadelmann B and Frey C. Geschichten des Gelingens – Gleichstellungsmassnahmen von Hochschulen im Dialog. University of Bern, Mar. 8, 2023.
Chaudhry, S., Zurbriggen, R., Preza, M., Kämpfer, T., Kaethner, M., Memedovski, R., Scorrano, N., Hemphill, A., Doggett, J.S., Lundström-Stadelmann, B. Dual inhibition of the
Echinococcus multilocularis
energy metabolism. International Conference of Parasitology (ICOPA), Copenhagen, DNK, Aug. 21-26, 2022.
Invited Presentation: Lundström-Stadelmann B. Novel approaches for the treatment of alveolar echinococcosis. Meeting of the Swiss Network of Echinococcosis, online, May 16, 2022.
Invited Presentation: Lundström-Stadelmann B. Novel approaches for the treatment of the fox tapeworm
Echinococcus multilocularis
. Mini symposium on the occasion of the retirement of Prof. Peter Deplazes, University of Zürich, Jan 20, 2022.
Invited Presentation: Lundström-Stadelmann B. Novel approaches for the treatment of the fox tapeworm
Echinococcus multilocularis
. Seminar on Drug Sciences. University of Basel, online, Nov 3, 2021.
Invited Presentation: Lundström-Stadelmann B. Novel treatment options against echinococcosis. Joint annual meeting 2021 of the Swiss Societies for Infectious Diseases (SSI), Hospital Hygiene (SSHH) with fibs/SIPI, Tropical Medicine and Parasitology (SSTMP) and the Swiss Society of Tropical and Travel Medicine (SSTTM), Montreux, CH, Sept. 2/3, 2021.
Invited Presentation: Lundström-Stadelmann B and CF Frey. Impulsreferat zum Topsharing an der Universität Bern, University of Bern, CH, online, Mar. 8, 2021.
Lundström-Stadelmann, B. Invited Presentation: Mefloquine and derivatives against
Echinococcus multilocularis
. Anthelmintics IV meeting, Santa Monica Bay, CA, Feb. 6, 2020.
Invited Presentation: Lundström-Stadelmann B. Mefloquine and derivatives against
Echinococcus multilocularis
. Anthelmintics IV meeting, Santa Monica Bay, CA, Feb. 6, 2020.
Invited seminar on new appraoches in anti-infective therapy: Lundström-Stadelmann B. Novel drug treatments against parasites: the example of
Echinococcus multilocularis
, University of Rennes, F, Nov. 28, 2019.
Ritler, D., Rufener, R., Li, J.V., Kämpfer, U., Bühr, C., Schürch, S., Lundström-Stadelmann, B. Identification of novel drug targets in
Echinococcus multilocularis
by metabolomics. Drug Design and Development Seminar (DDDS), Justus-Liebig Universität Giessen, Germany, Mar. 26-29, 2019.
Seminar on new approaches in anti-infective therapy: Lundström-Stadelmann B. To live or let die: novel chemotherapeutical treatments against the parasitic disease alveolar echinococcosis, University of Rennes, F, Nov. 22, 2018.
Presentation for interview Professor in Parasitology: Helminth control: from the field to the molecule and back, Vetsuisse Bern, CH, May 31, 2018.
Lundström-Stadelmann B. To live or let die: novel treatments against parasitic diseases. Habilitation lecture, Vetsuisse Faculties Bern and Zürich, Bern, Switzerland, Mar. 15, 2018.
Ritler, D., Rufener, R., Li, J., Lundström-Stadelmann, B.. The metabolism of
Echinococcus multilocularis
. World Congress in Echinococcosis, Algiers, ALG, Oct. 4-7, 2017.
Lundström-Stadelmann, B., Rufener, R., Dick, L., Gorgas, D., Marreros, N., Joekel, D., Küster, T., de Souza, M.V.N., Hemphill, A. Activity of the anti-malarial mefloquine against
Echinococcus
. World Congress in Echinococcosis, Algiers, ALG, Oct. 4-7, 2017.
Rufener, R., Dick, L., Strübig, L., Hemphill, A., Lundström-Stadelmann, B. An old drug reused: the activity of buparvaquone against the fox tapeworm
Echinococcus multilocularis.
Joint annual meeting SSM, SSI, SSHH, SSTMP and SSTTM, Basel, CH, Aug. 30 – Sept. 1, 2017.
Stadelmann, B., and A. Hemphill. Present status of alternative treatment of human and murine AE. Treatment and follow-up of AE in human patients, Bern, CH, Feb. 11, 2016.
Stadelmann, B. Plenary talk: Repurposed drugs and novel drug targets for the treatment of echinococcosis. 16th World Congress in Echinococcosis, Bukarest, ROU, Oct. 1-3, 2015.
Stadelmann, B., Rufener, R., Spiliotis, M., Kunz, S., Aeschbacher, D., Müller, J., and A. Hemphill. A novel anti-malarial compound with promising activity against Echinococcus multilocularis interacts directly with Echinococcus calmodulin. 16th World Congress in Echinococcosis, Bukarest, ROU, Oct. 1-3, 2015.
Stadelmann, B., Aeschbacher, D., Huber, C., Spiliotis, M., Müller, J. and A. Hemphill. Profound activity of the anti-cancer drug bortezomib against
E. multilocularis
metacestodes identifies the proteasome as a novel drug target in cestodes. Joint meeting DGP und SGTP. Zürich, CH, Jul. 16-19, 2014.
Stadelmann, B., Aeschbacher, D., Huber, C., Spiliotis, M., Müller, J. and A. Hemphill. Inhibition of
E. multilocularis
by Bortezomib – The proteasome as a novel target in cestodes. Innovation for the Management of Echinococcosis. Besançon, FRA, Mar. 27-29, 2014. (poster prize)
Stadelmann, B., Maayeh‘, S., Hoeppner, M.P., Eteti, C.M., Andersson, M.K., Ankarklev, J., Zamani, N., Grabherr M. and S.G. Svärd. Transcriptional changes of human intestinal epithelial cells upon infection with the parasite
Giardia intestinalis
reveal the role of NFKB and AU-rich elements in the early onset of giardiasis. 5
th
international
Giardia
and
Cryptosporidium
conference. Uppsala, SWE, May 27-30, 2014.
Invited seminar: The role of arginine in
Giardia
infection. Institute of Parasitology, University of Bern, CH, Aug. 2012.
Stadelmann, B., Jerlström-Hultqvist J., Merino C., Ankarklev J., Einarsson E. and S. Svärd. The role of arginine during
Giardia
infection. IV International Cryptosporidium & Giardia Conference. Wellington, NZ, Jan. 31-Feb. 3, 2012.
Stadelmann, B. The role of arginine in giardiasis. Protozoa meeting. Uppsala, SWE, Dec. 12, 2011.
Invited seminar: To be or not to be: The importance and applications of EmPGI in alveolar echinococcosis, Swiss Society of Tropical Medicine and Parasitology (SSTMP), annual meeting, Basel, CH, Nov. 2011.
Invited seminar:
Echinococcus multilocularis
(rävens dvärgbandmask) and alveolar echinococcosis. Swedish Institute for Infectious Disease Control (SMI), Stockholm, SWE, Nov. 2011.
Invited seminar:
Echinococcus multilocularis
and alveolar echinococcosis in Switzerland. Swedish Veterinary Agency (SVA), Uppsala, SWE, Feb. 2011.
Stadelmann, B., Jerlström-Hultqvist, J. and S. Svärd. Arginine deiminase and ornithine carbamoyl transferase as pathogenicity factors in giardiasis. SGTP meeting, Spiez, CH, Oct. 28/29, 2010.
Stadelmann, B., Scholl, S., Küster, T., Müller, J. and A. Hemphill. Small scale
in vitro
screening for new compounds against
Echinococcus multilocularis.
ICOPA XII, Melbourne, AUS, Aug. 15-20, 2010.
Stadelmann, B., Scholl, S., Küster, T., Müller, J. and A. Hemphill. Small scale
in vitro
screening for new compounds against
Echinococcus multilocularis
. DGP meeting, Düsseldorf, DEU, Mar. 16-19, 2010.
Stadelmann, B., Gottstein, B. and A. Hemphill. The host-parasite interface of alveolar echinococcosis and phosphoglucose isomerase (PGI). DGP meeting, Hamburg, DEU, Mar. 5-7, 2008.
Stadelmann, B., Deutsch, U., Gottstein, B. and A. Hemphill.
Echinococcus multilocularis
phosphoglucose isomerase (EmPGI): a moonlighting enzyme? SGTP meeting, Vevey, CH, Oct. 23-25, 2008.
Stadelmann, B., Scholl, S., Müller, J. and A. Hemphill.
Echinococcus multilocularis
phosphoglucose isomerase (EmPGI): a moonlighting enzyme? PhD Symposium, Bern, CH, Jan. 28, 2009.
Stadelmann, B., Naguleswaran, A., Gottstein, B., Hemphill, A. The laminated layer of
Echinococcus multilocularis
and phosphoglucose isomerase (PGI): studies on the host-parasite interface. 22nd International Congress on hydatidology, Athens Hilton, GRC, May 15-19, 2007.
Stadelmann, B., Hemphill, A. Characterization of laminated layer protein in
Echinococcus multilocularis
metacestodes. Annual meeting of the Swiss Society of Tropical Medicine and Parasitology. Swiss Tropical Institute, Basel, CH, Sept. 22-23, 2006.
Conference contributions presented by group members and/or collaborators
Wiedemar N, Gliga DS; Galat M, Preza M, Kaethner M, Frey CF, Lundström-Stadelmann B. Tools for investigation of drug resistance and screening of new compounds in the liver fluke
Fasciola hepatica
. 24
th
Drug Design & Development Seminar (DDDS) of the German Society for Parasitology, Würzburg, GER, Mar. 12-15, 2024. (P)
Preza M, Hiller L, Dietrich N, Lundström-Stadelmann B. Niclosamide ethanolamine against the fox tapeworm,
Echinococcus multilocularis
. 24
th
Drug Design & Development Seminar (DDDS) of the German Society for Parasitology, Würzburg, GER, Mar. 12-15, 2024. (P)
Benazzouz S, Kaethner M, Preza M, Kaempfer T, Zumstein P, Tamponi C, Varcasia A, Hemphill A, Brehm K, Lundström-Stadelmann B.
In vitro
drug screening cascade for
Echinococcus granulosus
. 24
th
Drug Design & Development Seminar (DDDS) of the German Society for Parasitology, Würzburg, GER, Mar. 12-15, 2024.
Bartetzko A, Zumstein P, Preza M, Lundström-Stadelmann B. Response to alveolar echinococcosis: Screening of the MMV Pandemic Response Box revealed a novel promising compound. 24
th
Drug Design & Development Seminar (DDDS) of the German Society for Parasitology, Würzburg, GER, Mar. 12-15, 2024. (P)
Zumstein P, Bartetzko A, Preza M, Nyffeler C, Mathis D, Lundström-Stadelmann B. Investigation of the malate dismutation pathway as a potential drug target in
Echinococcus mutlilocularis
. 24
th
Drug Design & Development Seminar (DDDS) of the German Society for Parasitology, Würzburg, GER, Mar. 12-15, 2024. (P)
Kaempfer T, Preza M, Hayoz M, Aebi Y, Kaethner M, Zumstein P, Largiader C, Brehm K, Lundström-Stadelmann B. Assessment of triclabendazole treatment against
E. multilocularis
. 24
th
Drug Design & Development Seminar (DDDS) of the German Society for Parasitology, Würzburg, GER, Mar. 12-15, 2024.
Kaethner M, Zumstein P, Przea M, Bartetzko A, Grossenbacher P, Lochner M, Schürch S, Regnault C, Villalobos Ramirez D, Lundström-Stadelmann B. Investigation of the threonine metabolism of
Echinococcus multilocularis
: EmTDH as a potential drug target against alveolar echinococcosis. 24
th
Drug Design & Development Seminar (DDDS) of the German Society for Parasitology, Würzburg, GER, Mar. 12-15, 2024.
Bartetzko A, Zumstein P, Preza M, Lundström-Stadelmann B. Screening of the MMV Pandemic Response Box against
Echinococcus multilocularis
reveals novel potential chemotherapeutics. Bern Parasitology Meeting, Bern, Feb. 2, 2024. (P)
Zumstein P, Bartetzko A, Preza M, Nyffeler C, Mathis D, Lundström-Stadelmann B. Investigation of the malate dismutation pathway as a potential drug target in
Echinococcus mutlilocularis
. Bern Parasitology Meeting, Bern, Feb. 2, 2024. (P)
Bartetzko A, Zumstein P, Preza M, Nyffeler C, Mathis D, Lundström-Stadelmann B. Cutting off the oxygen: Metabolic changes and differential gene expression depending on oxygen condition in
E. multilocularis
. Swiss Society of Tropical Medicine and Parasitology Students Meeting, Schwarzenberg, CH, Nov. 9/10, 2023. *** Best-presentation award***
Kaempfer T, Lundström-Stadelmann B.
In vitro
culture and treatment of
Taenia crassiceps
metacestodes. Swiss Society of Tropical Medicine and Parasitology Students Meeting, Schwarzenberg, CH, Nov. 9/10, 2023.
Galat M, Moré G, Mikharovskyi G, Malyuk M, Ovchinnikova A, Kovalenko G, Joeres M, Schares G, Lundström-Stadelmann B, Frey CF. The first
Toxoplasma gondii
genotyping from sheep slaughtered for human consumption in Ukraine. Annual meeting of the Swiss Society of Tropical Medicine, Basel, CH, Sept. 7/8, 2023.
Preza M, Kaethner M, Kaempfer T, Zumstein P, Tamponi C, Varcasia A, Hemphill A, Brehm K, Lundström-Stadelmann B. Advancing in drug discovery against
Echinococcus granulosus sensu stricto:
development and utilization of impartial
in vitro
screening assays. Annual meeting of the Swiss Society of Tropical Medicine, Basel, CH, Sept. 7/8, 2023.
Wiedemar N, Gliga DS, Preza M, Galat M, Kaethner M, Frey CF, Lundström-Stadelmann B. Triclabendazole resistance in Swiss Fasciola hepatica. Annual meeting of the Swiss Society of Tropical Medicine, Basel, CH, Sept. 7/8, 2023. (P)
Kaethner M, Zumstein P, Preza M, Grossenbacher P, Lochner M, Schürch S, Regnault C, Villalobos Ramirez D, Lundström-Stadelmann B. Investigation and inhibition of the threonine metabolism of
Echinococcus multilocularis
. Annual meeting of the Swiss Society of Tropical Medicine, Basel, CH, Sept. 7/8, 2023.
Zumstein P, Bartetzko A. Preza M, Kaethner M, Scorrano N, Kämpfer T, Lundström-Stadelmann B. Screening of the MMV Pandemic Response Box agianst
Echinococcus multilocularis
reveals novel potential chemotherapeutics. Annual meeting of the Swiss Society of Tropical Medicine, Basel, CH, Sept. 7/8, 2023. (P)
Kaempfer T, Preza M, Scorrano N, Kaethner M, Hayoz M, Aebi Y, Largiader C, Brehm K, Lundström-Stadelmann B. Assessment of triclabendazole treatment against
E. multilocularis
. XXIX World Congress of Echinococcosis, Bishkek, KYR, Aug. 28-30, 2023.
Preza M, Kaethner M, Kaempfer T, Zumstein P, Tamponi C, Varcasia A, Hemphill A, Brehm K, Lundström-Stadelmann B. Advancing in drug discovery against
Echinococcus granulosus sensu stricto:
development and utilization of impartial
in vitro
screening assays. XXIX World Congress of Echinococcosis, Bishkek, KYR, Aug. 28-30, 2023.
Kaempfer T, Gliga DS, Wiesner M, Basso W, Lundström-Stadelmann B.
In vitro
culture and treatment of
Taenia crassiceps
metacestodes. European Veterinary Parasitology College, Paris, F, June 30, 2023. (P)
Kaethner M, Zumstein P, Preza M, Grossenbacher P, Lochner M, Schürch S, Regnault C, Villalobos Ramirez, Lundström-Stadelmann B. Investigation and inhibition of the threonine metabolism of
Echinococcus multilocularis
. GCB Symposium University of Bern, CH, June 29, 2023.
Kaempfer T, Preza T, Scorrano N, Kaethner M, Hayoz M, Aebi Y, Largiader C, Brehm K, Lundström-Stadelmann B. Assessment of triclabendazole treatment against
E. multilocularis
. GCB Symposium University of Bern, CH, June 29, 2023. (P)
Kaethner M, Preza M, Kaempfer T, Zumstein P, Tamponi C, Varcasia A, Hemphill A, Brehm K, Lundström-Stadelmann, B. Objective
in vitro
drug testing for
Echinococcus granulosus
. 30
th
annual meeting of the German Society for Parasitology, DE, Mar. 15-17, 2023.
Kaethner M, Zumstein P, Preza M, Grossenbacher, P, Lochner, M, Schürch, S, Regnault, C, Villalobos Ramirez, D, Lundström-Stadelmann, B. The Achilles’ heel of the fox tapeworm? - Investigation of the threonine metabolism of
Echinococcus multilocularis
. 30
th
annual meeting of the German Society for Parasitology, DE, Mar. 15-17, 2023.
Zumstein P, Preza M, Kaethner M, Kaempfer T, Lundström-Stadelmann B. Screening of the MMV Pandemic Response Box against
E. multilocularis
. Swiss Society of Tropical Medicine and Parasitology Students Meeting, Bern, CH, Nov. 9, 2022.
Kaethner M, Grossenbacher P, Lochner M, Schürch S, Regnault C, Villalobos Ramirez D, Zumstein P, Lundström-Stadelmann B. Starving a deadly parasite: Investigation and inhibition of the threonine metabolism of the fox tapeworm
Echinococcus multilocularis
. Swiss Society of Tropical Medicine and Parasitology Students Meeting, Bern, CH, Nov. 9, 2022.
Kämpfer T, Przea M, Scorrano N, Kaethner M, Hayoz M, Yebi Y, Largiader C, Brehm K, De Brot S., Lundström-Stadelmann, B. Assessment of triclabendazole treatment against
E. multilocularis
. Joint annual conference of the Swiss Society of Tropical Medicine and Swiss Society of Tropical and Travel Medicine, Bern, CH, Nov. 10/11, 2022.
Preza M, Kaethner M, Kaempfer T, Tamponi C, Varcasia A, Lundström-Stadelmann B.
In vitro
drug screening against
Echinococcus multilocularis
and
E. granulosus
. Joint annual conference of the Swiss Society of Tropical Medicine and Swiss Society of Tropical and Travel Medicine, Bern, CH, Nov. 10/11, 2022.
Kaethner M, Grossenbacher P, Lochner M, Schürch S, Regnault C, Villalobos Ramirez D, Zumstein P, Lundström-Stadelmann B. Hungry for threonine: metabolomics in
Echinococcus multilocularis
. Joint annual conference of the Swiss Society of Tropical Medicine and Swiss Society of Tropical and Travel Medicine, Bern, CH, Nov. 10/11, 2022.
Kaethner M, Grossenbacher P, Lochner M, Schürch S, Regnault C, Villalobos Ramirez D, Lundström-Stadelmann B. The Achilles’ heel of the fox tapeworm? Investigation of the threonine metabolism of
Echinococcus multilocularis
. Parasitic Helminths: New Perspectives in Biology and Infection, Hydra, GRC, Aug. 28-Sept. 2, 2022. (P)
Kaethner M, Preza M, Kämpfer T, Tamponi C, Varcasia A, Lundström-Stadelmann B.
In vitro
drug screening cascade for
Echinococcus granulosus.
International Conference of Parasitology (ICOPA), Copenhagen, DNK, Aug. 21-26, 2022. (P)
Kaethner M, Grossenbacher P, Lochner M, Schürch S, Regnault C, Villalobos Ramirez D, Lundström-Stadelmann B. The Achilles’ heel of the fox tapeworm? Investigation of the threonine metabolism of
Echinococcus multilocularis
. International Conference of Parasitology (ICOPA), Copenhagen, DNK, Aug. 21-26, 2022. (P)
Preza M, Kaethner M, Kämpfer T, Scorrano N, Lundström-Stadelmann B. The metabolism of
Echinococcus multilocularis
under new drug testing. International Conference of Parasitology (ICOPA), Copenhagen, DNK, Aug. 21-26, 2022. (P)
Stettler M, Lotz C, Probst A, Hofmann D, Marreros N, Hofer A, Lundström-Stadelmann B, Frey CF, Keiser J, Hoby S. Pharmacokinetics of praziquantel in European pond turtles (
Emys orbicularis
). Zoo and Wildlife Conference, Emmen, NL, May 24-28, 2022.
Kaethner M, Grossenbacher P, Lochner M, Schürch S, Regnault C, Villalobos Ramirez D, Lundström-Stadelmann B. The Achilles’ heel of the fox tapeworm? Investigation of the threonine metabolism of Echinococcus multilocularis. GCB Symposium, online, Bern, Jan 27, 2022. (P)
Kämpfer T, Preza M, Chaudhry S, Kaethner M, Scorrano N, Lundström-Stadelmann B. Albendazole against
E. multilocularis
.
Swiss Society of Tropical Medicine and Parasitology Students Meeting, Schwarzenberg, CH, Oct. 21/22, 2021.
Kaethner M, Grossenbacher P, Lochner M, Schürch S, Regnault C, Villalobos Ramirez D, Lundström-Stadelmann B. The Achilles’ heel of the fox tapeworm? Investigation of the threonine metabolism of
Echinococcus multilocularis.
Swiss Society of Tropical Medicine and Parasitology Students Meeting, Schwarzenberg, CH, Oct. 21/22, 2021.
Autier B, Manuel C, Lundström-Stadelmann B, Girard J-P, Gottstein B, Samson M, Robert-Gangneux F, Dion S. IL-33 has a detrimental role in the progression of alveolar echinococcosis in a mouse model. European Mulicolloqium of Parasitology (EMOP), Belgrade, SRB, Oct. 12-16, 2021. (P)
Kaethner M, Grossenbacher P, Lochner M, Schürch S, Regnault C, Villalobos Ramirez D, Lundström-Stadelmann B. The Achilles’ heel of the fox tapeworm? Investigation of the threonine metabolism of
Echinococcus multilocularis
. European Mulicolloqium of Parasitology (EMOP), Belgrade, SRB, Oct. 12-16, 2021.
Chaudhry S, Zurbriggen R, Doggett S, Lundström-Stadelmann B. Dual inhibition of the
Echinococcus multilocularis
energy metabolism. European Mulicolloqium of Parasitology (EMOP), Belgrade, SRB, Oct. 12-16, 2021.
Memedovski R, Rufener R, Zurbriggen R, Braga S, Heller M, Müller J, Vinicius Nora de Souza M, Lundström-Stadelmann B. Activity and mechanism of action of meflqouine derivatives against
Echinococcus
. European Mulicolloqium of Parasitology (EMOP), Belgrade, SRB, Oct. 12-16, 2021.
Invited presentation: Memedovski R, Rufener R, Chaudhry S, Kaethner M, Müller J, Lundström-Stadelmann B. Asessment of mitochondrial respiration in
Echinococcus multilocularis
germinal layer cells by Seahorse Mini Analyzer. Seahorse Seminar Day and User Meeting, Bucher Biotech, Sept. 22, 2021.
Chaudhry S, Zurbriggen R, Dogget S, Lundström-Stadelmann B. Dual inhibition of the Echinococcus multilocularis energy metabolism. Joint annual meeting 2021 of the Swiss Societies for Infectious Diseases (SSI), Hospital Hygiene (SSHH) with fibs/SIPI, Tropical Medicine and Parasitology (SSTMP) and the Swiss Society of Tropical and Travel Medicine (SSTTM), Montreux, CH, Sept. 2/3, 2021.
Kaethner M, Grossenbacher P, Lochner M, Schürch S, Regnault C, Ramírez DV, Lundström-Stadelmann B. The Achilles’ heel of the fox tapeworm? Investigation of the threonine metabolism of Echinococcus multilocularis. Joint annual meeting 2021 of the Swiss Societies for Infectious Diseases (SSI), Hospital Hygiene (SSHH) with fibs/SIPI, Tropical Medicine and Parasitology (SSTMP) and the Swiss Society of Tropical and Travel Medicine (SSTTM), Montreux, CH, Sept. 2/3, 2021.
Memedovski R, Rufener R, Müller J, Zurbriggen R, de Sousa MVN, Braga S, Heller S, Lundström-Stadelmann B. Mefloquine based analogs evaluated against
Echinococcus multilocularis
metacestodes. Joint annual meeting 2021 of the Swiss Societies for Infectious Diseases (SSI), Hospital Hygiene (SSHH) with fibs/SIPI, Tropical Medicine and Parasitology (SSTMP) and the Swiss Society of Tropical and Travel Medicine (SSTTM), Montreux, CH, Sept. 2/3, 2021.
Memedovski R, Rufener R, Müller J, Zurbriggen R, de Sousa M, Lundström-Stadelmann B. Mefloquine based analogs evaluated against
Echinococcus multilocularis
metacestodes. Swiss Society of Tropical Medicine and Parasitology Students Meeting, online, CH, Nov. 4/5, 2020.
Karpstein T, Rufener R, Zurbriggen R, Bresson-Hadni S, Aebi Y and team, Hemphill A, Lundström-Stadelmann B. Is Maca the next super drug against alveolar echinococcosis? Or A reverse approach starting with a cured patient. Swiss Society of Tropical Medicine and Parasitology Students Meeting, online, CH, Nov. 4/5, 2020.
Kaethner M, Schürch S, Lundström-Stadelmann B. Starving a deadly parasite: Investigation and inhibition of the threonine metabolism of the fox tapeworm Echinococcus multilocularis. Swiss Society of Tropical Medicine and Parasitology Students Meeting, online, CH, Nov. 4/5, 2020.
Jebbawi F, Bellanger A-P, Lunström-Stadelmann B, Rufener R, Dosch M, Goepfert C, Gottstein B, Millon L, Grandgirard D, Leib SL, Beldi G, Wang J. Innate and adaptive immune responses following PD-L1 immune checkpoint blockade in treating chronic murine alveolar echinococcosis. 14th World Immune Regulation Meeting (WIRM), Davos (online), CH, Oct. 4-8, 2020.
Rufener, R. Fighting against
Echinococcus multilocularis
. Swiss Society of Tropical Medicine and Parasitology Students Meeting, Schwarzenberg, CH, Nov. 14-15, 2019.
Ritler D, Rufener R, Li J, Serricchio M, Kämpfer U, Bühr C, Schürch S, Bütikofer P, Lundström-Stadelmann B. Identification of novel drug targets in
Echinococcus multilocularis
by metabolomics. Joint annual meeting 2019 SGI / SGInf / SGSH / SGTP / SGTRM, Lausanne, CH, Sept. 18-20, 2019. (P)
Jebbawi, F., Bellanger, A., Lundström-Stadelmann, B., Rufener, R., Dosch, M., Belid, G., Millon, L., Gottstein, B., Wang, J. Innate and adaptive immunity interactions following PD-1/PDL-1 immune checkpoint blockade in murine alveolar echinococcosis. Joint annual meeting 2019 SGI / SGInf / SGSH / SGTP / SGTRM, Lausanne, CH, Sept. 18-20, 2019.
Feucherolles, M., Poppert, S., Endriss, Y., Marti, H., Hermosilla, C., Lundström-Stadelmann, B., Utzinger, J., Becker, S.L. Application of matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry in diagnostic helminthology: a proof-of-concept study. Conference on Tropical Medicine and Global Health, Munich, DEU, Apr. 4 -6, 2019.
Rufener, R., Zurbriggen, R., Dick, L., Ritler, D., Hemphill, A., Lundström-Stadelmann, B. Screening of the MMV Pathogen Box reveals the cytochrome bc1 complex as a drug target in
Echinococcus multilocularis
. Drug Design and Development Seminar (DDDS), Justus-Liebig Universität Giessen, DEU, Mar. 26-29, 2019.
Ritler, D., Rufener, R., Li, J.V., Lundström-Stadelmann, B.
In vitro
metabolomic studies on the
Echinococcus multilocularis
metacestode. Swiss Society of Tropical Medicine and Parasitology Students Meeting, Sigriswil, CH, Nov. 1-2, 2018.
Rufener, R., Dick, L., D’Ascoli, L., Ritler, D., Hizem, A., Wells, T., Hemphill, A., Lundström-Stadelmann, B. Targeting the mitochondrial complex III in
Echinococcus multilocularis
. Swiss Society of Tropical Medicine and Parasitology Students Meeting, Sigriswil, CH, Nov. 1-2, 2018.
Ritler, D., Rufener, R., Li, J.V., Lundström-Stadelmann, B.
In vitro
metabolomic studies on the
Echinococcus multilocularis
metacestode. Joint Annual Meeting 2018 SSI | SSHH | SSTMP | SSTTM. Interlaken, CH, Sept. 13-14, 2018. (P, poster flash)
Rufener, R., Dick, L., Ritler, D., Hemphill, A., Lundström-Stadelmann, B.
Echinococcus multilocularis
: from drug screenings to the energy metabolism. 28
th
annual meeting of the German Society of Parasitology, Berlin, DEU, Mar. 21-24, 2018.
Ritler, D., Rufener, R., Li, J., Lundström-Stadelmann, B. Starving a deadly parasite:
in vitro
metabolomic studies on the
Echinococcus multilocularis
metacestode. 28
th
annual meeting of the German Society of Parasitology, Berlin, DEU, Mar. 21-24, 2018.
Hemphill, A., Lundström-Stadelmann, B., Rufener, R., Dick, L., Ritler, D., Gottstein, B. Drugs or immunotherapy: what is best for the future? World Congress in Echinococcosis, Algiers, ALG, Oct. 4-7, 2017.
Rufener, R., Dick, L., Strübig, L., Hemphill, A., Lundström-Stadelmann, B. Screening the pathogen box and repurposing buparvaquone against
Echinococcus multilocularis
. World Congress in Echinococcosis, Algiers, ALG, Oct. 4-7, 2017.
Ritler, D., Rufener, R., Bouvier, J., Sager, H., Hemphill, A., Lundström-Stadelmann, B. Development of a movement-based
in vitro
screening for new anti-cestodal compounds. World Congress in Echinococcosis, Algiers, ALG, Oct. 4-7, 2017. (P, poster prize)
Ritler, D., Rufener, R., Bouvier, J., Sager, H., Hemphill, A., Lundström-Stadelmann, B. Motility-based
in vitro
screening for the identification of new anti-cestodal compounds. Joint annual meeting SSM, SSI, SSHH, SSTMP and SSTTM, Basel, CH, Aug. 30 – Sept. 1, 2017. (P)
Rufener, R., Kunz, S., Ritler, D., Hemphill, A., Lundström-Stadelmann, B. Drugs against alveolar echinococcosis: New faces and old friends. Joint annual meeting SSM, SSI, SSHH, SSTMP and SSTTM, Basel, CH, Aug. 30 – Sept. 1, 2017. (P)
Ma’ayeh, S.Y, Stadelmann, B., Knörr, L., Sköld, K., Hoeppner, M., Grabherr, M. and S. G. Svärd. Transcriptional Profiling of Differentiated CaCo-2 Intestinal Epithelial Cells Response to
Giardia Intestinalis
during Early Onset of
in vitro
Interactions: Insights into the Pathways of Cytokine Production and Regulation. VI International Giardia and Cryptosporidium Conference, Havana City, CUBA, Apr. 26 – 28, 2017.
Liu, J., Peirasmaki, D., Ma’ayeh, S., Stadelmann, B., Hellman, L. and S. Svärd. Secreted
Giardia intestinalis
cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines. VI International Giardia and Cryptosporidium Conference, Havana City, CUBA, Apr. 26 – 28, 2017. (P)
Peirasmaki, D., Ferella, M., Höppner, M., Campos, S., Ankarklev, J., Stadelmann, B., Grabherr, M. and S. Svärd. High Cysteine Membrane Proteins are highly up-regulated during
Giardia
-host cell interactions. VI International Giardia and Cryptosporidium Conference, Havana City, CUBA, Apr. 26 – 28, 2017. (P)
Rufener, R., Strübig, L., Ritler, D., Hemphill, A. and B. Lundström-Stadelmann. Drugs against alveolar echinococcosis: the hunt goes on. Joint annual meeting SSI, SSHH, SSTMP and FMH, Montreux, CH, Sept. 1-2, 2016. (P)
Ritler, D., Rufener, R., Bouvier, J., Sager, H., Hemphill, A. and B. Lundström-Stadelmann. Development of a movement-based in vitro screening for new anti-cestodal compounds. Joint annual meeting SSI, SSHH, SSTMP and FMH, Montreux, CH, Sept. 1-2, 2016. (P)
Rufener, R., Aeschbacher, D., Hemphill, A., Stadelmann, B. Focus on anti-malarials for the treatment of alveolar echinococcosis: a new drug on the horizon? COST Action 1307: Chemotherapy Towards Diseases Caused by Endoparasites. Meeting of Working Groups 1 and 4. Porto, May 5-6, 2016 (P).
Hemphill, A., Rufener, R., Stadelmann, B.: Screening of the Open Source malariabox reveals novel potential drug candidate for the treatment of alveolar echinococcosis. 27
th
meeting of the German Society for Parasitology, Göttingen, Mar. 9-12, 2016.
Rufener, R., Aeschbacher, D., Hemphill, A. and B. Stadelmann. Focus on an anti-malarial drug against
Echinococcus multilocularis
- a new treatment on the horizon? Joint meeting DGP und SGTP. Zürich, CH, Jul. 16-19, 2014. (P)
Spiliotis, M., Stadelmann, B., Boubaker, G., Hirsch, P., Gottstein, B. and A. Hemphill. Axenic culture of
Echinococcus multilocularis
primary cells: a novel tool to carry out high-throughput screening assays on bioactive molecules. Joint meeting DGP und SGTP. Zürich, CH, Jul. 16-19, 2014. (P)
Ma'ayeh
1
, S., Stadelmann
1
, B., Molin, E., Hoeppner, M., Eteti, C., Andersson, M., Ankarklev, J., Zemani, N., Grabherr, M. and S. Svärd. Transcriptional profiling of differentiated Caco-2 intestinal epithelial cells response to
Giardia intestinalis
during early onset of in vitro interactions: insights into the pathways of cytokine production and regulation. V International Giardia and Cryptosporidium Conference, Uppsala, SWE, May 27-30, 2014. (P)
Spiliotis, M., Stadelmann, B., Hirschi, P., Gottstein, B. and A. Hemphill. Axenic culture of
Echinococcus multilocularis
primary cells: a novel tool to carry out high-throughput screening assays on bioactive molecules. Innovation for the Management of Echinococcosis. Besançon, FRA, Mar. 27-29, 2014. (P)
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